Month: December 2013
A trial has begun of a vaccine to treat an aggressive form of brain cancer.
The first patient in Europe has received the treatment at King’s College Hospital in London. Robert Demeger, 62, was diagnosed with the condition earlier this year.
The personalised vaccine is designed to teach his body’s immune system to fight the tumour cells.
King’s is one of more than 50 hospitals – the rest are in the US – which are testing the treatment.
Mr Demeger, a stage and TV actor, had to give up his role in the acclaimed National Theatre production of Othello when he began having seizures.
“I had an understudy and I said, if I get ill on stage just take over the line, but fortunately it never happened.
“Eventually I was diagnosed with a brain tumour and had surgery within a matter of days.”
Before his operation he was offered the chance to be the first patient in Europe to join the international trial.
Surgeons removed as much of his tumour as possible. It was incubated in a lab alongside dendritic cells – specialist immune cells taken from his blood.
The aim was to teach the cells to recognise the tumour. The resulting personalised vaccine was injected in his arm, with the hope that the cells will train others in the immune system to seek out and destroy the cancer.
He will receive 10 doses of the vaccine over the coming two years.
Keyoumars Ashkan, a neurosurgeon at King’s, is leading the UK arm of the trial. He says there is a pressing need for new and better treatments for brain cancers.
“Even if a tumour seems the same between two patients, the reality is they are very varied.
“So the ‘one-size fits all’ therapy is probably not optimal. There is a need to be able to deliver individualised treatment based on a patient’s own cancer type.”
The trial involves patients with glioblastoma, the most aggressive form of primary brain tumour, which affects around 1,500 people in Britain every year.
Average survival time is just 12-18 months. Two previous small studies of the DCVax therapy, in the US, found that it extended that to three years, without toxic side-effects. Twenty patients were involved and two of these have so far lived for 10 years.
Mr Ashkan stressed that the current trial, which will involve 300 patients, is needed to show whether the treatment is truly effective. Half will receive the personalised vaccine and the rest dummy injections.
“Until we get the results of this research, we will not know whether the therapy should be offered to all patients” he said.
Mr Demeger says he is delighted to be part of the research. “Anything that may give me a better chance, but also others, is worth taking part in” he said.
The surgery to remove his cancer affected his speech, because the tumour was sitting close to the part of the brain dealing with language.
So Mr Demeger, whose voice has been his livelihood, has had to re-learn how to communicate.
“I’d love to get back to acting. It’s my job.
“I’ve been working with a speech therapist and the head of voice at the National.
“Whether I’m back on stage in weeks or months I don’t know but I’m hopeful. ”
SOURCE: BBC NEWS
Netflix is testing a streaming video plan that lets subscribers save a buck every month in exchange for a couple sacrifices.
The $7 per month plan, discovered by AdWeek, lets users stream one video at a time in standard definition only. But right now, it’s only available to a small number of new subscribers. “Not all people will see this option and it may not be something we ever offer generally,” a Netflix spokeswoman told AdWeek.
Netflix’s regular $8 per month plan allows up to two streams at once on a single account, and supports high definition video as well. The company also offers a family plan for $12 per month, allowing up to four streams at once.
Aside from that family plan, which arrived in April, Netflix hasn’t touched its pricing since 2011, when the company split mail-order DVD rentals into a separate $8 per month service. (The…
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From the Winter Olympics to the Six Nations, the World Cup and the Commonwealth Games, BBC Sport picks out the key sporting events coming up in the next 12 months.
3-7: Cricket: Ashes fifth Test, Sydney
5-13: BDO World Darts Championships, Lakeside
4-5: FA Cup third round
7-8 & 21-22: League Cup semi-finals
10-13: Cricket: Women’s Ashes Test, Australia v England, Perth
12-19: Snooker: The Masters, Alexandra Palace
12, 17, 19, 24, 26: Australia v England ODIs
13-26: Tennis: Australian Open, Melbourne
19, 23, 26: Women’s Cricket: Australia v England ODIs
25-26: FA Cup 4th round
25-26: GB Athletics international, Glasgow
29, 31, 2 Feb: England v Australia T20 internationals (men and women)
31, 1, 2 Feb: Tennis: Davis Cup World Group, GB v USA, San Diego
1: Six Nations: Wales v Italy, France v England
2: Six Nations: Ireland v Scotland
2: NFL: Superbowl, East Rutherford, New Jersey
4-9: Tennis: Fed Cup, GB in Budapest
7-23: Winter Olympics, Sochi
8: Six Nations: Ireland v Wales, Scotland v England
9: Six Nations: France v Italy
8-9: Athletics: British Indoor Championships, Sheffield
15: FA Cup 5th round
15: Athletics: British Indoor Grand Prix, Birmingham
18/19, 25/26: Football: Champions League 2nd round
20, 27: Football: Europa League 2nd round
21: Six Nations: Wales v France
22: Six Nations: Italy v Scotland, England v Ireland; World Club Challenge, Wigan Warriors v Sydney Roosters, Sydney
26-2 March: World Track Cycling, Colombia
26: Cricket: West Indies v England ODI
2, 5: Cricket: West Indies v England ODI
2: Football: League Cup final
5: Football: England v Denmark friendly
7-16: Winter Paralympics, Sochi
7-9: Athletics: World Indoor Championships, Poland
8: FA Cup quarter-finals
8: Six Nations: Ireland v Italy, Scotland v France
9: Six Nations: England v Wales
9, 1, 13: Cricket: West Indies v England T20s
11-14: Racing: Cheltenham Festival
13, 20 : Football: Europa League 3rd round
15: Six Nations: Italy v England, Wales v Scotland, France v Ireland
16: F1: Australian Grand Prix, Melbourne
16: Football: Scottish League Cup final
16-31: Cricket: ICC World T20s, Bangladesh
20-23: MotoGP: Qatar Grand Prix, Losail
23-6 Apr: Cricket: Women’s World T20, Bangladesh
28-31: Rowing World Cup, Sydney
30: F1: Malaysia Grand Prix, Kuala Lumpur
29: Racing: Dubai World Cup
1-2, 8-9: Champions League quarter-finals
3, 10: Football: Europa League quarter-finals
5: Racing: Grand National, Aintree
6: F1: Bahrain Grand Prix, Sakhir
6: Rowing: Boat Race, London
10-13: Golf: The Masters, Augusta
12-13: FA Cup semi-finals
13: London Marathon
13: MotoGP: Grand Prix of the Americas, Austin, Texas
20: F1: Chinese Grand Prix, Shanghai
20-5 April: World Snooker Championship, Sheffield
22-23, 29-30: Champions League semis
24, 1 May: Europa League semis
26-27: Heineken Cup semi-finals
27 MotoGP: Argentina Grand Prix
3-4: Racing: Guineas Festival, Newmarket
4: MotoGP: Spanish Grand Prix, Jerez
7-11: Badminton Horse Trials
9: Athletics: Diamond League, Doha
9-1 June: Cycling: Giro d’Italia
11: F1: Spanish Grand Prix
11: End of Premier League season
14: Europa League final, Turin
17: FA Cup final
17: Scottish Cup final
17: Athletics: Diamond League, Shanghai
17-18: Diving: World Championships, London
18: MotoGP: France Grand Prix, Le Mans
22-25: Golf: PGA Championship, Wentworth
23: Rugby Union: Challenge Cup final, Cardiff
24: Football: Champions League final, Lisbon
24: Rugby Union: Heineken Cup final, Cardiff
24: League Two Play-off final, Wembley
25: F1: Monaco Grand Prix, Monte Carlo
25-8 June: Tennis: French Open, Roland Garros
25: League One Play-off final, Wembley
26: Championship Play-off final, Wembley
30-1 June: Rowing: European Championships, Belgrade
31-15 June: Hockey: World Cup (men’s and women’s), Hague
1: MotoGP: Italy Grand Prix, Mugello
5: Athletics: Diamond League, Rome
7: Racing: The Derby, Epsom
7: Athletics: Diamond League, Eugene
7: Rugby Union: New Zealand v England, South Africa v Wales, United States v Scotland, Argentina v Ireland
8: F1: Canadian Grand Prix, Montreal
9-14: Tennis: Queen’s
11: Athletics: Diamond League, Oslo
12-13 July: Football: World Cup, Brazil
12-16: Cricket: England v Sri Lanka 1st Test, Lord’s
12-15: Golf: US Open, Pinehurst
14: Rugby Union: New Zealand v England, South Africa v Wales, Canada v Scotland, Argentina v Ireland
14: Athletics: Diamond League, New York
15: MotoGP: Catalonia GP, Barcelona
16-21: Tennis: Eastbourne
17-21: Racing: Royal Ascot
20-24: Cricket: England v Sri Lanka 2nd Test, Headingley
20-22: Rowing World Cup, France
21: Rugby Union: New Zealand v England, Argentina v Scotland
21-22: Athletics: European Team Championships, Germany
22: F1: Austrian Grand Prix (Spielberg)
22, 25, 28, 31, 3 June: Cricket: England v Sri Lanka ODI series
23-6 July: Tennis: Wimbledon
26-29: Equestrian: Hickstead
27-29: Athletics: British Championships, Birmingham
28 June: Rugby Union: South Africa v Scotland
28: MotoGP: Netherlands Grand Prix, Assen
3: Athletics: Diamond League, Lausanne
6: F1: British Grand Prix, Silverstone
5: Athletics: Diamond League, Paris
5-27: Cycling: Tour de France
9-13: Cricket: England v India, 1st Test, Trent Bridge
11-12: Athletics: Diamond League, London
11-13: MotoGP: German Grand Prix, Sachsenring
11-13: Rowing World Cup, Lucerne
17-20: Golf: The Open, Royal Liverpool
17-21: Cricket: England v India, 2nd Test, Lord’s
18: Athletics: Diamond League, Monaco
20: F1: German Grand Prix, Hockenheim
20: Athletics: London Anniversary event
22-26: Horse Racing: Glorious Goodwood
23-3 Aug: Commonwealth Games, Glasgow
27-31: Cricket: England v India 3rd Test, Southampton
27: F1: Hungarian Grand Prix
29-2 Aug: Racing: Glorious Goodwood
1-4: Golf: Women’s Open, St Andrews
1-17: Women’s Rugby World Cup, France
7-11: Cricket: England v India, 4th Test, Old Trafford
7-10: Golf: PGA Championship, Valhalla
10: MotoGP: Indianapolis GP
12-17: Athletics: European Championships, Zurich
15-19: Cricket: England v India, 5th Test, Oval
17: MotoGP: Czech Republic GP, Brno
16-28: World Youth Games, China
16: Premier League football season starts
21: Athletics: Diamond League, Stockholm
18-23: IPC European Athletics, Swansea
18-24: Swimming: European Championships, Berlin
23: Rugby League: Challenge Cup final, Wembley
23-14 Sept: Cycling: Tour of Spain
24: Athletics: Diamond League, Birmingham
24: F1: Belgium Grand Prix, Spa
24-31: Rowing: World Championships, Amsterdam
25-8 Sept: Tennis: US Open, New York
25, 27, 30, 2, 5 Sept: Cricket: England v India, ODIs
28: Athletics: Diamond League, Zurich
31: MotoGP: British GP, Silverstone
2, 5: Cricket: England v India, ODIs
5: Athletics: Diamond League, Brussels
7: F1: Italian Grand Prix, Monza
7: Athletics: Great North Run
7: England v India T20 International
8-21: Sailing: World Championships, Santander
13: Racing St Leger, Doncaster
14: MotoGP: San Marino GP, Misano
21: MotoGP: Aragon GP, Aragon (Spain)
20-28: Cycling: World Road Championships, Spain
21: F1: Singapore Grand Prix
26-28: Golf: Ryder Cup, Gleneagles
28: MotoGP: Brazil GP, Brasilia
3-12: Gymnastics: World Championships, China
5: F1: Japanese Grand Prix, Suzuka
12: MotoGP: Japan GP, Motegi
11: Rugby League: Super League Grand Final, Old Trafford
12: F1: Russian Grand Prix, Sochi
19: MotoGP: Australia GP, Phillip Island
18: October Horse racing, Champions Day, Ascot
26: MotoGP Malaysian GP, Sepang
31-1 Nov: Racing: Breeders’ Cup, Santa Anita, California
2: F1: US Grand Prix, Austin
4: Racing: Melbourne Cup
8: Rugby Union: England v New Zealand, Ireland v South Africa, Scotland v Argentina, Wales v Australia
9: F1: Brazilian Grand Prix, Sao Paolo
9: MotoGP: Valencia
10-17: Tennis: ATP World Finals, London
15: Rugby Union: England v South Africa, Scotland v New Zealand, Wales v Fiji
22: Rugby Union: England v Samoa, Ireland v Australia, Scotland v Tonga, Wales v New Zealand
23: F1: Abu Dhabi Grand Prix, Yas Marina
29: Rugby Union: England v Australia, Wales v South Africa
3-7: Swimming: World Short Course Championships, Doha
26: Racing: King George VI Chase, Kempton Park.
The list will be updated with further fixtures and events as they are announced; dates and venues are subject to change
Manny Norté, the go to party DJ for huge international stars like Jay Z, Rihanna, Trey Songz, Beyonce, Snoop Dogg, Pharrell & Dr Dre, is in Ghana for a week-long tour.
Dec 28 – Devino midnight-3am
Dec 29 – Shisha Lounge 6pm-2am
Dec 30 – Firefly midnight-3am
Dec 31 – Movenpick Hotel 11.30pm-3.30am
Jan 1 – Rockstone’s 12.30-3am
Jan 2 – Hollywood Boulevard midnight-3am
Jan 3 – Santoku 8-11pm & Vienna City midnight-3am
He has played across the UK at the most esteemed night clubs. Around the world, he’s played in Norway, Sweden, Malaysia, Hong Kong, Russia, Spain & France to name but a few. He was also asked to DJ at the F1 Grand Prix in Bahrain.
Manny has a MOBO award for best club DJ.
Manny is also a radio regular who has presented a weekend show on BBC Radio 1Xtra as well as being on Kiss FM and Choice FM with a mixshow every Friday night/Saturday morning with regular live shows recorded at London’s Jazz Cafe and featuring guests like Eve, Wizkid, Fuse ODG, Lethal Bizzle, Eliza Doolittle and many more.
Now on Capital Xtra (formerly Choice FM) Monday to Friday, his experiences & understanding of the urban scene & music over the past two decades is unpatrolled. Couple this with his inimitable presenting style and it’s no wonder Manny Norté is such an in demand talent.